14c urea breath test kit for h.Pylori test

Specifications
h p Test Kit is the reagent set for [14c]-Urea Breath Test for the diagnosis of Helicobacter pylori infection. a test kit

Product Description:

The kit is the reagent set for [14c]-Urea Breath Test for the diagnosis of Helicobacter pylori infection. a test kit consists of a [14c]-Urea capsule and a breath card. To conduct the test, the subject orally administers the [14c]-Urea capsule and then exhales to a breath card after a specific interval. The analysis and detection of Helicobacter pylori is done through the measurement of the breath sample with ionization technology.

The principle of [14c]-Urea Breath Test
The [14c]-Urea Breath Test (ubt) is based on the detection of the enzyme urease, produced by Helicobacter pylori. Since urease is not present in normal human tissues, and since other urease-producing bacteria do not colonize the stomach, the presence of urease in the stomach can be equated with Helicobacter pylori infection.

In the presence of urease, orally administered 14c urea will be hydrolyzed into ammonia and 14co2.14co2 is absorbed into the blood circulation and exhaled by the lung. The presence of a significant amount of 14co2 in the exhaled breath indicates active Helicobacter pylori infection.

The [14c]-Urea Breath Test offers advantages as below:

Accurate: Sensitivity 95%, specificity 95%-100%.
Comfortable: Non-invasive, no endoscopic tube insertion, well tolerated by patients.
Convenient: Near-patient testing, analysis made on site, minimal inconvenience for patients.
Safe: Negligible radiation burden, no risk of inter-patient cross-infection.
Simple: Easy operation, no special handling required.
Swift: Entire test finished in 25 minutes.

The procedure of [14c]-Urea Breath Test
The test is conducted two hours after meal or with an empty stomach in the morning
1. Swallow a 14c Urea capsule with water
2. Sit for 15 minutes
3. Blow into a breath card for 3-5 minutes
4. Test the breath card with the analyzer
5. The result will be printed after 5 minutes

[Specification]
1.40 grains(27.8kBq(0.75μCi)/ grain) of [14c]-Urea capsules / package
2.40 pieces of breath cards/package

The gmp certified [14c]-Urea capsule contains the minimum dose of 0.75μCi [14c]-Urea in the world.

The breath card has been granted two patents. Its ergonomic design features an anti-inhale safety mouthpiece which effectively ensures against inhalation during exhaling.